Learn more about Bridelia uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Bridelia. Asas, Assas, Bridelia cathartica, Bridelia ferruginea , Bridelia grandis, Bridelia micrantha, Bridelia. In present study we explore dose dependent effects of Bridelia ferruginea on hematological parameters. The hematological responses of albino. A review of Bridelia ferruginea, Combretum glutinosum and Mitragina inermis plants used in zootherapeutic remedies in West Africa: historical.
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The serum ALP levels are also related to the status and function of hepatic cells and according to the literature, an increase in serum ALP may occur as a result of increased synthesis, in the presence of increasing biliary pressure.
They were air dried and the dried samples were grinded with the aid of milling machine into powder and the resulting powder kept in a clean air tight container.
Concordance of toxicity of pharmaceuticals in humans and in animals. Effects of the Aqueous extract of Bridelia ferruginea stem bark on carrageenan-induced odema and granuloma tissue formation in rats and mice. This observation may be due to the variation in the length of administration of the plant extract.
To receive news and publication updates for Evidence-Based Complementary and Alternative Medicine, enter your email address in the box below. Ferurginea samples were collected via ocular puncture with the aid of a capillary tube into EDTA ethylenediaminetetraacetic acid bottles and heparinized bottles for respective hematological and blood chemistry analysis.
Modulatory activity of antioxidants against the toxicity of rifampicin in vivo. The reaction mixture 3 mL contained 0.
West African Plants – A Photo Guide – Bridelia ferruginea Benth.
Investigation ferruinea the haematologic and hepatoxic effects of rinba-cin in rats. Serum catalase activity was determined according to the method of Beers and Sizer as described by Usoh et al. When increased therapeutic benefit comes at increased cost.
The hypoglycemic property of Bridelia ferruginea. Our current results show that inhibition of PGE 2nitric oxide, and the proinflammatory cytokines plays significant roles fsrruginea the earlier observed in vivo actions of B. Anti-microbial activity of Bridelia ferruginea leaves extracts. Intraperitoneal acute toxicity The mice were randomly divided into five groups of five animals per group. COX-1 is expressed constitutively in most cell types, whereas expression of COX-2 is induced by various factors including inflammatory cytokines and is responsible for the maintenance of the inflammatory process.
Taylor and Francis; Blackwell Scientific Publication; feeruginea The caudal epididymis was carefully isolated and minced with scissors to release the sperm. Complement-inhibiting constituent of Bridelia ferruginea stem bark.
The results obtained revealed that methanol extract was the most effective on Bacillus substilis and Escherichial ferruglnea while ethanol extract was most effective on Staphylococcus aureus.
A 1 in 20 dilution of semen was carried out using sodium bicarbonate-formalin diluting fluid. Hence the extract of Bridelia ferruginea must be rarely used and if its use is inevitable, antioxidant brirelia must be incorporated.
Bovine serum albumin BSA, Sigma was used as a standard.
Measurement briddelia the activity of serum antioxidant enzymes and malondialdehyde MDA Determination of superoxide dismutase activity EC 1. I of drugs Rang et al. Urea, the end product of protein metabolism, and its concentration is influenced by the rate of excretion, while creatinine is the waste product of muscle metabolism.
Table of Contents Alerts. Journal List Interdiscip Toxicol v. It is usually a gnarled shrub, which sometimes reach the size of a tree when grown in a suitable environment.
There were no significant differences in the animals and organ weights, hematological and bricelia parameters in the treated groups compared to the control group.
The results further revealed that the extract caused an increase in the body weight of rats in the test groups, compared to the rats in the ferrugihea group. In spite of the varied ethnopharmacological applications of B.
Acute toxicity LD 50 testing has been widely used, though often criticized as a parameter for assessing toxicity Lorke, ; Klaassen, ; Timbrel, Bridelia ferruginea stem bark was collected from a tree growing on the Ferrugihea of Ibadan Campus, Nigeria. Discussion Acute toxicity LD 50 testing has been widely used, though often criticized as a parameter for assessing toxicity Lorke, ; Klaassen, ; Timbrel, Confluent monolayers were passaged routinely by trypsinisation. Determination of lipid peroxidation EC Malondialdehyde, an index of lipid peroxidation, was determined by adding 1.
The micrographs of the brain sections obtained from untreated rats and rats treated with various doses of aqueous stem bark extract of Bridelia ferruginea. Journal of Applied Sciences and Environmental Sanitation.
The Effect Of Bridelia ferruginea Bark Extract On Some Pathogenic Micro-Organisms
Increased or decreased organ weight was observed as a sensitive indicator of organ toxicity by known toxicants Dioka et al. One hundred and eighty microlitres of medium was removed from every well without disturbing the cell clusters. The total sperm count, motile sperm count and normal sperm morphologic features have been reported as indices of fertility in males Small et al.
Acute toxicity study Oral acute toxicity The mice were randomly divided into five groups of five animals per group. Experiments were performed at least three times and in triplicate. The mice were randomly divided into five groups of five animals per group. Mycelia growth in the control.
Acute and sub-chronic 28 days oral toxicity evaluation of hydroethanolic extract of Bridelia ferruginea Benth root bark in male rodent animals. Briefly, laparotomy was done to expose the reproductive tract. Sperm count A 1 in 20 dilution of semen was carried out using sodium bicarbonate-formalin diluting fluid.
The plates were incubated at 37 0 c for 24 hrs.
However, this observation is paradoxical as higher doses ferrugiinea not decrease the sperm count. Malondialdehyde MDAa breakdown product, is a measure of lipid hydroperoxides, causing lipid peroxidation. Malondialdehyde was calculated using the molar extinction coefficient for malondialdehyde-thiobarbituric acid complex of 1. Phytochemical constituents of some Nigerian Medicinal Plants.