Palmoplantar keratodermas (PPKs) are a diverse entity of disorders that are characterized by abnormal thickening of the skin on the palms and soles. What are the other Names for this Condition? (Also known as/Synonyms). Acquired Palmoplantar Keratoderma; Acquired PPK. Paraneoplastic palmoplantar keratoderma (PPK) is an acquired dermatosis that presents with hyperkeratosis of the palms and soles in association with visceral.
|Published (Last):||3 November 2014|
|PDF File Size:||5.52 Mb|
|ePub File Size:||20.69 Mb|
|Price:||Free* [*Free Regsitration Required]|
Website author — Dr Tim Cunliffe read more. The vast majority are associated with adenocarcinoma of the stomach, but other malignancies sometimes found include other GI tract tumours, lung, uterus, ovaries, and urinary tract Tripe palms – the appearance differs to that of keratoderma with thickened velvety palms that have the appearance of tripe.
Any image downloaded must only be used for teaching purposes and not for commercial use. Palmoplantar keratodermas PPKs are a diverse entity of disorders that are characterized by abnormal thickening of the skin on the palms and soles.
Any findings suggestive of underlying conditions should be aggressively evaluated and treated. Keratoderma may be hereditarywith symptoms presenting in early childhood, or acquired when it presents in later life.
To facilitate such evaluations, this review categorizes the acquired PPKs as: Clinical classification Keratoderma can be defined by its clinical appearance, although there is often overlap: This website is non-profit and holds the images for educational purposes only.
If findings are consistent with a hereditary keratoderma, then a genetics consultation should be considered.
All named individuals and organisations maintain copyright for the relevant images. The cutaneous features usually pre-date the diagnosis of the cancer. Please click on images to enlarge or download. Please follow this link if you have any high-quality images that you can contribute to the website.
Palmoplantar keratoderma | Primary Care Dermatology Society | UK
Given the numerous possible underlying causes for acquired PPKs, evaluation of patients presenting with acquired PPK can be a perplexing task. A painful paronychia develops with no evidence of bacterial or fungal infection. It usually affects the sole of the feet around the margins of the heel and under the metatarsal heads.
This chapter provides a practical overview of keratoderma, and is set out as below: Rarely keratoderma can be associated with malignancy. They can be very effective for some patients, but cannot be used in fertile women due to their teratogenicity. Notice and credit must be given to the PCDS or other named contributor.
Aetiology Clinical findings Images Investigations Management. Keratoderma of the soles and acanthosis nigricans of the hands in a patient with bladder carcinoma.
Acquired palmoplantar keratoderma.
In cases where tripe palms occur without AN, lung cancers are usually responsible. If no such etiology is evident, then conservative treatment options include topical keratolytics urea, salicylic acid, lactic acidrepeated physical debridement, topical retinoids, topical psoralen plus UVA, and topical corticosteroids.
Axial CT images showing multiple polypoidal enhancing mass lesions with surface calcifications, in the urinary bladder. Palmoplantar keratoderma is a term used to define a marked thickening of the skin on the palms and soles, either as a focal entity, or diffuse.
The palms of the hands may be affected with discrete, centrally placed palmoplanfar. In terms of treatment, the most successful results occur when the underlying etiology is diagnosed and treated.
In order to avoid the possibility of overlooking an underlying etiology and to eliminate excessive testing, we present acquied algorithm for assessing patients presenting with acquired PPK.
If no pertinent findings are identified after a history and a physical examination, laboratory and radiology studies should be undertaken in a systematic, logical fashion. It is often associated with acanthosis nigricans AN. Web Design – Mode Ten Designs.
Occasionally keratoderma can affect other parts of the body It can be difficult to differentiate between the different types of keratoderma, however, the management principles are similarand as such the key diagnostic elements are to exclude the rare malignant or other systemic causes.
Keratoderma can be inherited, acquired, and rarely, paraneoplastic ie secondary to an internal malignancy.
Acquired palmoplantar keratoderma.
There is usually a well-defined erythematous border The two conditions vary in their histological features Several others types have been described. The first step should include a comprehensive history and a physical examination, including a complete skin examination.
Some people with focal palmoplantar keratoderma also have abnormalities of the fingernails and toenails There are several inherited typeswhich are all rare.